Waynesburg from Whitacre Hill
The caption on this undated postcard picture says "View from Whitacre Hill, Waynesburg."
Although the area has changed a great deal, the scene looks similar to the view looking north across the railroad tracks and creek from what is now N. Main Street. Whitacre Hill could reference the old Whitacre Fireproofing Co., but I don't know where this business was located.
If this does indeed show a northerly view, the cluster of houses at the top of the photo is the intersection of Rt. 43 and Mottice Road. A mile or two up Mottice Road -- left as you are looking at the photo -- is where the Peter Mottice homestead was.